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TPC2 expression level and melanin content are inversely correlated in MNT-1 cells and primary human melanocytes. (A) Melanin content was determined in MNT-1 cells (black bars) and primary human melanocytes (white bars) subjected to control siRNA and TPC2 siRNA. (B) Melanin content was determined in MNT-1 cells transfected with GFP and TPC2-GFP plasmids.
