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TPC2 regulates Ca2+ release from melanosomes. (A) Spinning-disk confocal fluorescence microscopy images of live wild-type and TPC2-KO MNT-1 cells expressing tyrosinase-GCaMP6-Cherry. (Scale bars, 5 µm.) (B) The green/red fluorescence intensity ratio was calculated for wild-type and TPC2-KO MNT-1 cells expressing tyrosinase-GCaMP6-Cherry (n = 17 and 19 cells, respectively).
