Figure 4.

Alcian blue/periodic-acid Schiff staining of articular cartilage samples from osteoarthritis rabbits with or without 60, 100 and 200 µmol/l ketamine. The Alcian blue staining is specific for the cartilaginous tissues while the red periodic-acid Schiff staining indicates the subchondral bone and other tissues. Dose-dependent increases in the thickness of blue-stained cartilaginous tissues subsequent to ketamine treatment were observed: (A) Normal saline; (B) Ket₆₀; (C) Ket₁₀₀; and (D) Ket₂₀₀. Magnification ×200. The cartilaginous tissues were stained blue and other tissues were stained red.