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Upregulation of miR-221 or downregulation of miR-486 promotes cell migration and invasion. (A) Wound healing assay and (B) Transwell migration assay were used to measure cell migratory capacity. (C) Transwell invasion assay was used to measure cell invasive capacity. Magnification, ×200. Data are presented as the mean ± standard deviation. *P<0.05, **P<0.01, ***P<0.001. miR, microRNA; NC, negative control.
