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. Author manuscript; available in PMC: 2017 May 15.
Published in final edited form as: Brain Res. 2016 Mar 17;1639:200–213. doi: 10.1016/j.brainres.2016.01.058

Figure 2.

Figure 2

Plasma levels of 17β-estradiol (E2) as measured by the Elecsys assay (mean ± sd). E2 pellets (0.72 mg, Innovative Research of America) produced supraphysiologic levels > 2000 pg/mL E2 as early as 30 minutes after implantation with a peak at 2 hours of > 3200 pg/mL. E2 levels remained elevated (> 2500 pg/mL) through 6 hours. For E2 treated MCAO animals included in this study, E2 at time of euthanasia (42d) was reduced to high physiologic levels (60 pg/mL).