Table 1. Comparison of CTCF binding sites in hematopoietic stem and progenitor cell (HSPC) and erythroid cell chromatin with CTCF binding in multiple cell types.
Cell Type | Data Source* | Number of CTCF Binding Sites Identified | Number of Common CTCF Sites in HSPC Cells | Number of Common CTCF Sites in Erythroid Cells |
---|---|---|---|---|
HSPC | This report | 50,798 | 23,105 (47%) | |
Erythroid | This report | 49,417 | 23,183 (45%) | |
CD14 | Broad | 40,187 | 16,497 (32%) | 24,867 (50%) |
GM12878 | Broad | 37,570 | 19,064 (38%) | 29,316 (59%) |
H1ES | Broad | 54,489 | 19,747 (39%) | 29,898 (61%) |
HCM | UWashington | 44,259 | 19,799 (39%) | 31,253 (63%) |
HMF | UWashington | 51,723 | 19,392 (38%) | 31,512 (64%) |
HUVEC | UWashington | 66,858 | 22,240 (44%) | 36,453 (74%) |
NHEK | Broad | 53,766 | 19,292 (38%) | 31,723 (64%) |
K562 | UWashington | 54,076 | 22,021 (43%) | 34,091 (69%) |
* ENCODE ChIP-seq data from multiple cell types obtained from the UCSC database were compared to binding sites in primary human HSPC progenitor cells and primary nucleated human erythroid cells. Percents are the fraction of common sites divided by the total number of HSPC or erythroid CTCF sites.