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. 2016 May 24;11(5):e0155946. doi: 10.1371/journal.pone.0155946

Fig 5. UA down-regulated c-Myc and p21 protein levels in human STS cells.

Fig 5

Synovial sarcoma SW982 and leiomyosarcoma SK-UT-1 cells were treated with vehicle (DMSO) or UA (5–30 μM) for 9 or 12 h, respectively. Upper panels show immunoreactive bands of c-Myc and p21 proteins in representative immunoblots of SW982 cells treated without or with UA for 9 h. Columns represent the ratio of the c-Myc to β-actin immunoreactivity in SW982 cells (left panel) or p21 to β-actin immunoreactivity in both cell types (right panel). Each value represents mean ± SEM of 3 independent experiments normalized to vehicle-treated cells (taken as 100%). **P < 0.01 and ***P < 0.001 versus vehicle-treated cells.