Table 2.
Clinical predictors of seizures
| Patient characteristic | Without seizure (n = 61) | With seizure (n = 8) | Univariate odds OR [95 % CI] | Multivariate odds OR [95 % CI] |
|---|---|---|---|---|
| Demographics | ||||
| Age > median, n (%) | 30 (49.2 %) | 6 (75.0 %) | 3.1 [0.58–16.58] | – |
| Clinical presentation | ||||
| Thick cisternal blood (F3), n (%) | 44 (72.1 %) | 7 (87.5 %) | 2.7 [0.31–23.66] | – |
| High clinical grade (HH4-5), n (%) | 23 (39.0 %) | 2 (28.6 %) | 0.6 [0.11–3.50] | – |
| Intraparenchymal hemorrhage, n (%) | 14 (23.3 %) | 1 (12.5 %) | 0.5 [0.05–4.15] | – |
| Intraventricular hemorrhage, n (%) | 43 (70.5 %) | 5 (62.5 %) | 0.7 [0.15–3.23] | – |
| Hydrocephalus, n (%) | 33 (54.1 %) | 5 (62.5 %) | 1.4 [0.31–6.45] | – |
| MCA aneurysm location, n (%) | 5 (8.2 %) | 3 (37.5 %) | 6.7 [1.23–36.74]* | 5.0 [0.78–29.13] |
| ACA aneurysm location, n (%) | 5 (8.2 %) | 0 (0 %) | – | – |
| Craniotomy, n (%) | 40 (65.6 %) | 5 (62.5 %) | 0.9 [0.19–4.02] | – |
| Clinical suspicion for seizures, n (%) | 26 (42.6 %) | 5 (62.5 %) | 2.2 [0.49–10.24] | – |
| Electrophysiology | ||||
| AED at time of EEG, n (%) | 36 (59.0 %) | 2 (25.0 %) | 0.2 [0.04–1.24]** | 0.3 [0.04–1.58] |
| cEEG duration (days), mean (SD) | 5.5 (3.8) | 6.6 (4.6) | t(67) = 0.72, p = 0.5 | – |
MCA middle cerebral artery, ACA anterior cerebral artery, AED anti-epileptic drug
*
p ≤ 0.05,
**
p ≤ 0.01