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Development of seizures, wet-dog shakes, and myoclonic jerks following administration of 4AP in four rats. (A) Occurrence of seizures over time after 4AP administration. (B, C) Raster plots and corresponding frequency distribution histograms showing the occurrence of behavioral symptoms over time. Note that occurrence of wet-dog shakes (B) is higher after 4AP administration compared to myoclonic jerks that increased in occurrence later after 4AP administration (C).
