Figure 2. Distributions and patterns of changes over the 52 weeks on the ADAS-cog-K in the imputed placebo and total galantamine groups. The scores on the ordinate axis display changes from baseline ADAS-cog-K scores. The natural decline in cognition for the imputed placebo group (green, square-dotted) was estimated using the Stern equation, where initial baseline ADAS-cog-K scores of the study participants (N=66) were used to predict deterioration. The total galantamine group (pink, diamond-dotted) (N=66) showed significant therapeutic efficacy on cognition at each evaluation point (i.e., 4, 13, 26, 39, and 52 weeks), compared to the imputed placebo group. ^*p<0.05, ^**p<0.01. SE: standard error, ADAS-cog-K: Korean version of the Alzheimer's Disesase Assessment Scale-cognitive subscale.