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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Heart Rhythm. 2016 Jan 25;13(6):1326–1334. doi: 10.1016/j.hrthm.2016.01.024

Figure 3.

Figure 3

Ameliorative effects of isoproterenol (0.2 μM) in an arterially perfused canine left ventricular model of early repolarization syndrome. Simultaneously recorded epicardial (Epi1, Epi2) and endocardial (Endo) action potentials, together with pseudo-ECG positioned in the transmural axis. A: Control. B: 20 min after addition of the Ito agonist NS5806 (12μM) to the coronary perfusate. C: After 16 min exposure to verapamil (2μM), in addition to NS5806 (12μM). D: 3 minutes later. E: 5 min after the start of isoproterenol (0.2μM) infusion. F: 5 min after the discontinuation of isoproterenol infusion.