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. Author manuscript; available in PMC: 2017 May 15.
Published in final edited form as: Exp Cell Res. 2016 Mar 23;344(1):95–102. doi: 10.1016/j.yexcr.2016.03.022

Figure 3.

Figure 3

Real-time PCR exhibited reductions of Axin2 and Cyclin D1 transcription. (A) Significant reduction in Axin2 transcription was observed with raloxifene alone or in combination with 0.1 μM PX-866. No reduction was observed with highest PX-866 concentration. (B) Significant reduction of Cyclin D1 transcription was observed with each PX-866 concentration in combination with 1.0 μM raloxifene. No decrease in Cyclin D1 was observed with raloxifene alone. Values represent averages from 3 independent experiments + SEM. * p < 0.05. ** p < 0.01.