. Author manuscript; available in PMC: 2017 May 15.

Published in final edited form as: Exp Cell Res. 2016 Mar 23;344(1):95–102. doi: 10.1016/j.yexcr.2016.03.022

Table 1.

Significant relative levels of mRNA, protein and phosphorylated protein following three days of treatment of MCF-7 cells with raloxifene and/or PX-866.

Micromolar Treatment	TERT	p21	Cyc D1	Axin 2	LIF	HB EGF	DEC1
Control	1.00	1.00	1.00	1.00	1.00	1.00	1.00
1.0 Raloxifene				0.328 ^*	0.158 ^*	0.338 ^*
0.4 PX-866
Raloxifene + 0.1 PX-866	0.396 ^*		0.398 ^*	0.260 ^*	0.283 ^*	0.370 ^*
Raloxifene + 0.4 PX-866	0.539 ^*		0.336 ^*
Raloxifene + 0.8 PX-866		2.76 ^*	0.356 ^*				1.95 ^*

Micromolar Treatment	pMDM2 protein
Control	1.00
1.0 Raloxifene
0.4 PX-866	0.379 ^*
Raloxifene + 0.1 PX-866	0.395 ^*
Raloxifene + 0.4 PX-866	0.385 ^*
Raloxifene + 0.8 PX-866	0.353 ^*

p < 0.5,

^**

p < 0.01