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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Semin Arthritis Rheum. 2016 Apr 8;45(6):648–655. doi: 10.1016/j.semarthrit.2016.04.001

Table 1.

Baseline demographic parameters and baseline clinical scores and their evolution over 1.5 years of subjects without (KL 0/1) versus with radiographic evidence of hip osteoarthritis (KL 2/3)

Parameter Kellgren/Lawrence score
(KL)
P-
value*
KL 0/1 KL 2/3
Group size (n) 36 18
Female sex (n; % of
group)
18 (50.0%) 5 (27.8%) .120
Age (years; mean ± SD) 43.7 ± 12.8 54.4 ± 11.2 .004
BMI (kg/m2; mean ±
SD)
23.9 ± 3.2 24.1 ± 3.2 .834
Hip side (left; n; % of
group)
18 (50.0%) 9 (50.0%) 1.000
Baseline Harris Hip
Score
(Median; IQR) 100 (96–100) 97 (88.5–100) 0.057
Baseline HOOS pain
score
(Median; IQR) 100 (95–100) 97.5 (78.5–
100)
0.041
Baseline HOOS other
symptoms
(Median; IQR) 97.5 (90–100) 95 (83.5–100) 0.284
Baseline HOOS
activities of daily living
(Median; IQR) 100 (97–100) 95 (83.5–100) 0.114
Baseline HOOS sports (Median; IQR) 100 (89–100) 93.5 (81–100) 0.044
Baseline HOOS quality
of life
(Median; IQR) 100 (81–100) 90 (81–100) 0.160
Evolution of Harris Hip
Score
Delta values
(median; IQR)
0 (−0.5–1) 0 (−6.5–1.5) 0.652
Worsening (n; % of
group)
7 (24.1%) 6 (37.5%) 0.494
Evolution of HOOS pain
score
Delta values
(median; IQR)
0 (0–0) −1.5 (−7.5–
8.5)
0.562
Worsening (n; % of
group)
6 (16.7%) 9 (50%) 0.010
Evolution of HOOS
other symptoms score
Delta values
(median; IQR)
0 (−3.5–5) −2.5 (−10–5) 0.295
Worsening (n; % of
group)
9 (25.0%) 9 (50.0%) 0.047
Evolution of HOOS
activities of daily living
Delta values
(median; IQR)
0 (0–0) 0 (−3–2) 0.419
Worsening (n; % of
group)
7 (19.4%) 8 (44.4%) 0.053
Evolution of HOOS
sports
Delta values
(median; IQR)
0 (0–0) 0 (−18.5–9.5) 0.724
Worsening (n; % of
group)
8 (22.2%) 6 (33.3%) 0.512
Evolution of HOOS
quality of life
Delta values
(median; IQR)
0 (0–0) −3.5 (−15.5–
14)
0.502
Worsening (n; % of
group)
8 (22.2%) 9 (50.0%) 0.038
*

Fisher’s exact test was used for categorical data presence/absence of abnormalities or progression yes/no), Student’s t test for numerical data, and the exact Mann-Whitney U test for nonparametric testing. Worsening of clinical scores is any change <0 of absolute Harris Hip Score or HOOS subscales over time.