Table 2.
Comparison of demographic and clinical characteristics between WBC quartiles (n = 1302)
| WBC quartiles, 1000 cells/uL
|
p value | ||||
|---|---|---|---|---|---|
| Q1, < 7.10 (n = 326) | Q2, 7.10 – 9.19 (n = 319) | Q3, 9.20 – 11.70 (n = 328) | Q4, > 11.70 (n = 329) | ||
| Age, median (IQR), y | 75 (65 – 81) | 75 (65 – 82) | 76 (65 – 83) | 74 (62 – 81) | 0.138 |
| Sex, male, n (%) | 193 (59.2) | 187 (58.6) | 175 (53.4) | 172 (52.3) | 0.171 |
| History of hypertension, n (%) | 256 (78.5) | 249 (78.1) | 267 (81.4) | 269 (81.8) | 0.526 |
| History of diabetes, n (%) | 83 (25.5) | 65 (20.4) | 66 (20.1) | 82 (24.9) | 0.207 |
| History of hypercholesterolemia, n (%) | 148 (45.4) | 138 (43.3) | 135 (41.2) | 121 (36.8) | 0.140 |
| Antiplatelet treatment, n (%) | 153 (46.9) | 150 (47.0) | 150 (45.7) | 161 (48.9) | 0.875 |
| Anticoagulant treatment, n (%) | 76 (23.3) | 71 (22.3) | 67 (20.4) | 69 (21.0) | 0.808 |
| Time from symptom onset to NCCT, median (IQR), h | 3.1 (1.6 – 6.8) | 4.0 (1.9 – 9.9) | 4.6 (1.9 – 8.4) | 5.1 (3.0 – 7.9) | 0.002 |
| Time from onset to blood sample, median (IQR), h | 2.4 (1.2 – 5.0) | 3.9 (1.8 – 8.3) | 3.5 (2.0 – 6.5) | 4.1 (2.3 – 6.5) | <0.001 |
| PLT count, median (IQR), 1000 cells/uL | 197 (154 – 240) | 221 (178 – 258) | 230 (191 – 277) | 255 (209 – 325) | <0.001 |
| aPTT, median (IQR), s | 26.3 (23.8 – 30.3) | 26.2 (23.7 – 29.1) | 26.1 (23.6 – 29.4) | 25.3 (23.1 – 29.0) | 0.091 |
| INR, median (IQR) | 1.1 (1.0 – 1.3) | 1.1 (1.0 – 1.3) | 1.1 (1.0 – 1.2) | 1.1 (1.0 – 1.2) | 0.620 |
| Baseline ICH volume, median (IQR), mL | 10 (4 – 26) | 11 (4 – 28) | 16 (6 – 36) | 22 (7 – 48) | <0.001 |
| Presence of IVH, n (%) | 122 (37.4) | 113 (35.4) | 152 (46.3) | 185 (56.2) | <0.001 |
| Hematoma Expansion, n (%) | 69 (21.2) | 47 (14.7) | 46 (14.0) | 45 (13.7) | 0.027 |
WBC indicates white blood cells; IQR, interquartile range; NCCT, computed tomography; PLT, platelet; aPTT, activated partial thromboplastin time; INR, international normalized ratio; ICH, intracerebral hemorrhage; IVH, intraventricular hemorrhage.