Table 1.
Clinical and demographic characteristics of the cohort.
| Low Risk (N=4,196) | Intermediate Risk (N=3,777) | High Risk (N=13,785) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Covariate | Chemotherapy | P-value | Chemotherapy | P-value | Chemotherapy | P-value | |||
| N | % | N | % | N | % | ||||
| 652 | (15.5) | 1,493 | (39.5) | 9,628 | (69.8) | ||||
| Age | <0.001 | <0.001 | <0.001 | ||||||
| <40 | 102 | (13.9) | 166 | (37.8) | 802 | (68.0) | |||
| 40–49 | 182 | (17.3) | 359 | (42.8) | 2,131 | (70.1) | |||
| 50–59 | 205 | (19.0) | 488 | (46.1) | 3,371 | (74.3) | |||
| 60–69 | 113 | (16.1) | 283 | (39.1) | 2,034 | (73.4) | |||
| ≥70 | 50 | (8.0) | 197 | (27.5) | 1,290 | (57.2) | |||
| Race | 0.03 | 0.67 | <0.001 | ||||||
| White | 571 | (16.2) | 1,258 | (39.7) | 8,158 | (70.4) | |||
| Black | 29 | (11.7) | 72 | (38.1) | 369 | (62.7) | |||
| Hispanic | 22 | (10.2) | 78 | (36.3) | 473 | (68.8) | |||
| Other/unknown | 30 | (14.8) | 85 | (41.7) | 628 | (68.6) | |||
| Insurance | 0.01 | <0.001 | <0.001 | ||||||
| Private | 450 | (17.2) | 987 | (43.3) | 6,368 | (72.1) | |||
| Medicaid | 34 | (14.7) | 81 | (44.0) | 426 | (72.1) | |||
| Medicare | 108 | (11.6) | 300 | (30.8) | 2,024 | (62.8) | |||
| Uninsured | 39 | (14.9) | 77 | (36.7) | 449 | (72.2) | |||
| Other government/unknown | 21 | (13.8) | 48 | (37.2) | 361 | (69.3) | |||
| Comorbidity | 0.99 | 0.17 | <0.001 | ||||||
| 0 | 358 | (15.5) | 818 | (39.9) | 5,800 | (70.8) | |||
| 1 | 60 | (15.7) | 157 | (44.0) | 909 | (71.0) | |||
| 2 | 15 | (16.7) | 28 | (35.0) | 166 | (61.7) | |||
| Unknown | 219 | (15.5) | 490 | (38.0) | 2,753 | (68.0) | |||
| Facility location | 0.10 | 0.01 | <0.001 | ||||||
| Eastern | 159 | (17.9) | 331 | (41.9) | 2,167 | (74.3) | |||
| Midwest | 223 | (15.4) | 543 | (41.1) | 3,358 | (71.8) | |||
| South | 180 | (15.2) | 414 | (39.0) | 2,451 | (67.7) | |||
| West | 90 | (13.4) | 205 | (34.1) | 1,652 | (64.3) | |||
| Facility Type | 0.75 | 0.02 | <0.001 | ||||||
| Community cancer | 40 | (13.9) | 90 | (35.9) | 579 | (68.0) | |||
| Comprehensive community cancer | 340 | (15.7) | 774 | (38.6) | 4,657 | (66.3) | |||
| Academic/research | 272 | (15.7) | 616 | (41.1) | 4,383 | (74.4) | |||
| Other | - | - | 13 | (68.4) | * | * | |||
| Urban/rural | 0.67 | 0.69 | 0.31 | ||||||
| Metropolitan | 542 | (15.8) | 1,209 | (39.5) | 7,868 | (69.7) | |||
| Urban | 79 | (14.4) | 197 | (40.6) | 1,198 | (71.5) | |||
| Rural | * | * | 21 | (32.8) | 141 | (70.9) | |||
| Unknown | 23 | (14.4) | 66 | (40.0) | 421 | (67.8) | |||
| Histology | <0.001 | <0.001 | <0.001 | ||||||
| Serous | 65 | (12.9) | 265 | (40.9) | 2,850 | (69.6) | |||
| Mucinous | 153 | (9.8) | 313 | (29.4) | 1,105 | (61.8) | |||
| Endometrioid | 397 | (20.9) | 826 | (45.3) | 2,625 | (71.1) | |||
| Clear cell | - | - | - | - | 2,466 | (74.3) | |||
| Transitional cell | * | * | * | * | 58 | (69.1) | |||
| Epithelial tumor NOS | 37 | (16.7) | 84 | (35.4) | 524 | (64.5) | |||
| Grade | - | - | <0.001 | ||||||
| 1 | 652 | (15.5) | - | - | 1,262 | (63.8) | |||
| 2 | - | - | 1,493 | (39.5) | 2,182 | (72.7) | |||
| 3 | - | - | - | - | 4,986 | (71.4) | |||
| Unknown | - | - | - | - | 1,198 | (65.6) | |||
| Stage | <0.001 | <0.001 | <0.001 | ||||||
| IA | 552 | (14.1) | 1,295 | (37.8) | 2,279 | (65.8) | |||
| IB | 100 | (37.0) | 198 | (56.3) | 355 | (68.3) | |||
| IC | - | - | - | - | 6,994 | (71.4) | |||
| Lymph nodes examined | 0.24 | 0.02 | <0.001 | ||||||
| Yes | 502 | (16.1) | 1,205 | (40.7) | 7,713 | (71.6) | |||
| No | 144 | (13.9) | 278 | (35.5) | 1,806 | (63.1) | |||
| Unknown | * | * | * | * | 109 | (72.7) | |||
*
Values censored due to small sample size