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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Am J Med. 2016 Feb 1;129(6):620–627. doi: 10.1016/j.amjmed.2016.01.016

Table 3. Risk for adverse clinical outcome according to patterns of hyponatremia development.

All-cause mortality Death or heart failure readmission
HR (95% CI) P-value HR (95% CI) P-value
Persistent hyponatremia 2.50 (1.50-4.19) <0.001 2.18 (1.60-2.97) <0.001
Decompensation hyponatremia 1.93 (0.97-3.85) 0.060 1.26 (0.80-1.98) 0.327
Treatment-induced hyponatremia 1.62 (0.96-2.73) 0.070 1.43 (1.06-1.93) 0.018