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. Author manuscript; available in PMC: 2017 Sep 25.
Published in final edited form as: N Biotechnol. 2015 Nov 24;33(5 Pt A):565–573. doi: 10.1016/j.nbt.2015.11.005

Fig. 3. Sequence analysis of selected clones.

Fig. 3

Specific CDR sequences were enriched during selection. The sequences identified with the highest frequency are labeled sequence A, B, and C. All other sequences were found at a frequency of less than 10%. (A) Oligonucleotide distribution of CDRs found against the EZH2 target after three rounds of biopanning shows a strong consensus in each CDR (represented as sequence A). (B) Oligonucleotide distribution after two rounds of biopanning against the EZH2 target. The same sequences A, B, and C found in round 3 were also identified in round 2. (C) The enriched sequences A, B, and C found after two and three rounds of panning against EZH2 protein fragment.