Table 2.
Tertiles of Adiponectin and Leptin for BE cases compared to GERD Controls and Screening Colonoscopy Controls with adjustment for age, gender, race, and waist to hip ratio.
| Tertiles | ||||
|---|---|---|---|---|
| 1 | 2 | 3 | p (trend) | |
|
BE cases vs. Colonoscopy controls
| ||||
| Adiponectin | ||||
| Range | ||||
| Men | <5.33 | 5.33-8.75 | >8.75 | |
| Women | <7.62 | 7.62-12.92 | >12.92 | |
| Cases | 36 | 52 | 45 | |
| Controls | 386 | 372 | 399 | |
| ORc95%CI)† | 1.0 (referent) | 1.49 (0.95, 2.35) | 1.20 (0.76, 1.92) | 0.45 |
| ORa (95%CI)‡ | 1.0 (referent) | 0.98 (0.55, 1.74) | 0.42 (0.22, 0.80) | 0.006 |
| Leptin | ||||
| Range | ||||
| Men | <5 | 5-12.24 | >12.24 | |
| Women | <13.65 | 13.65-30.72 | >30.72 | |
| Cases | 20 | 63 | 50 | |
| Controls | 408 | 366 | 383 | |
| ORc (95% CI) | 1.0 | 3.51 (2.08, 5.92) | 2.66 (1.55, 4.55) | 0.001 |
| ORa (95%CI) | 1.0 | 2.70 (1.48,4.94) | 1.57 (0.82, 3.04) | 0.22 |
|
BE cases vs. GERD controls | ||||
| Adiponectin | ||||
| Range | ||||
| Men | <5.33 | 5.33-8.75 | >8.75 | |
| Women | <7.62 | 7.62-12.92 | >12.92 | |
| Cases | 36 | 52 | 45 | |
| Controls | 48 | 46 | 41 | |
| ORc (95%CI) | 1.0 (referent) | 1.50 (0.84, 2.71) | 1.46 (0.80, 2.67) | 0.22 |
| ORa (95% CI) | 1.0 (referent) | 1.39 (0.70, 2.76) | 0.65 (0.31, 1.36) | 0.29 |
| Leptin | ||||
| Range | ||||
| Men | <5 | 5-12.24 | >12.24 | |
| Women | <13.65 | 13.65-30.72 | >30.72 | |
| Cases | 20 | 63 | 50 | |
| Controls | 39 | 46 | 50 | |
| ORc (95% CI) | 1.0 (referent) | 2.67(1.38, 5.16) | 1.94 (1.00, 3.79) | 0.12 |
| ORa (95% CI) | 1.0 (referent) | 2.72 (1.28, 5.74) | 1.32 (0.61, 2.88) | 0.66 |
†
ORc = crude odds ratio
‡
ORa = adjusted odds ratio