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. 2016 May 25;10:49. doi: 10.3389/fncom.2016.00049

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Copyright © 2016 Yang, Meijer, Doll, Buitenweg and van Gils.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Three ways the postsynaptic potential x⁰(t) (solid) can reach the threshold (dashed) when two pulses are applied. The above-threshold time ΔT may consist of one interval by crossing upon the second pulse only (A) or upon the first pulse staying above threshold until the second pulses (C). If the pulses are well separated in time ΔT consists of two intervals (B). Temporal properties are NoP = 2, IPI = 20 ms and PW = 0.525 ms, and the amplitude are varied, i.e., not equal to A₅₀.