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. 2015 Dec 1;52:550–560. doi: 10.1007/s12020-015-0809-1

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Increased IGF-I mRNA levels in femoral artery and elevated serum IL-6 and cholesterol concentrations in female LI-IGF-I^−/− mice. Male and female LI-IGF-I^−/− and control mice (n = 9–16/group) received an atherogenic (modified Paigen) diet from 6 months of age. a IGF-I mRNA levels in femoral artery and b hepatic triglyceride content at the end of the study in female and male mice. c IL-6, and d cholesterol, in serum before the start of the modified Paigen diet (baseline) and after 2 weeks of the diet in female mice. Values are given as means (SEM). p values were calculated using unpaired t tests