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. 2016 Apr 19;21(6):797–805. doi: 10.1038/mp.2016.46

Figure 4.

Figure 4

Minocycline treatment and chronic restraint stress affect the gut microbiome and chronic restraint stress changes the gut Firmicutes/Bacteroidetes (F/B) ratio. (a) Box and whiskers plot displayed the analysis of the differences of the main composition of the microbiota (Firmicutes to Bacteroidetes). Upper and lower quartiles defined the box with median midline, and the whiskers were assessed using Tukey's method. (b) Microbiota distribution at species level of taxon contributing to 97.5% of sample variations. Heatmap shows square root-transformed read counts for the 20 taxa determined by similarity percentage analysis. The dendrogram shows the clustering of genera based on Ward's hierarchical clustering method. Phyla are abbreviated as follows: Actinobacteria (A), Bacteroidetes (B), Firmicutes (F), Proteobacteria (P) and Verrocomicrobia (V).