Figure 7.

PBA reduced M-cone degeneration in KI mice. A, Representative M-opsin immunoreactivity in the superior retinas of 10-week-old WT and KI mice treated with PBA or saline. Scale bar, 20 μm. B, Total numbers of M-cones in the superior and inferior retinal sections of WT and KI mice treated with PBA or saline. C, Immunoblot analysis showing increase of M-opsin in KI mice treated with PBA. Asterisks indicate significant differences between PBA- and saline-treated KI mice (p ≤ 0.01). Error bars indicate SD (n = 4).