Figure 2.

Decreased MUA in medullary raphe and reduced breathing during seizure. A, Seizure induced by 2 s stimulation of HC. After the stimulus, fast polyspike activity is seen in the HC LFP. MUA from the medullary raphe shows marked suppression of neuronal firing during the seizure with gradual recovery in the post-ictal period. Respiratory trace shows breathing flow amplitude (proportional to volume) and rate both decreased markedly during the ictal and post-ictal periods. B, Expanded segments of data from baseline, seizure, post-ictal, and recovery periods from the boxed regions in A.