Skip to main content
. 2016 May 11;2016:6985903. doi: 10.1155/2016/6985903

Table 2.

Significantly different gene expression between children with and without DS.

Gene Gene IDa Gene name Mean RQ RQ log⁡2 p value
BDKRB1 623 Bradykinin receptor B1 0.0013 −9.6225 0.0003
LTA4H 4048 Leukotriene A4 hydrolase 0.0079 −6.9899 0.0005
ITGAM 3684 Integrin, alpha-M (complement component 3 receptor 3 subunit) 0.0364 −4.7811 0.0144
ADRB2 154 Adrenoceptor beta 2, surface 0.0543 −4.2037 0.0089
CD40LG 959 CD40 ligand 0.0737 −3.7613 0.0151
ITGB1 3688 Integrin, beta 1 0.0779 −3.6822 0.0399
TNFRSF1B 7133 Tumor necrosis factor receptor superfamily, member 1B 0.0829 −3.5917 0.0258
TBXAS1 6916 Thromboxane A synthase 1 (platelet) 0.1032 −3.2768 0.0428
PLCB4 5332 Phospholipase C, beta 4 8.7676 3.1322 0.0443
ICAM1 3383 Intercellular adhesion molecule 1 9.7116 3.2797 0.0268
HTR3A 3359 5-Hydroxytryptamine (serotonin) receptor 3A, ionotropic 9.8319 3.2975 0.0343
ALOX12 239 Arachidonate 12-lipoxygenase 10.6198 3.4087 0.0171
PLA2G5 5322 Phospholipase A2, group V 12.5688 3.6518 0.0423
PDE4C 5143 Phosphodiesterase 4C, cAMP-specific 19.2927 4.2700 0.0390
PLCD1 5333 Phospholipase C, delta 1 19.9510 4.3184 0.0449
PLA2G2D 26279 Phospholipase A2, group IID 21.3914 4.4190 0.0067
ADRB1 153 Adrenoceptor beta 1 24.2235 4.5983 0.0491
CACNA1D 776 Calcium channel, voltage-dependent, L type, alpha 1D subunit 25.3055 4.6614 0.0125
CASP1 834 Caspase 1, apoptosis-related cysteine peptidase 47.1421 5.5589 0.0479
VCAM1 7412 Vascular cell adhesion molecule 1 52.8885 5.7249 0.0243

aGene Identification second-base gene data, the National Center for Biotechnology Information (NCBI, http://www.ncbi.nlm.nih.gov/gene).