TABLE 1.
Characteristics of patients and non-Aspergillus invasive mold infections
| Characteristic | No. (%) of patients |
|---|---|
| Patients (n = 39) | |
| Male | 24 (62) |
| Age (median yr [range]) | 59 (5–76) |
| Underlying condition | |
| Hematologic malignancy | 22 (56) |
| Allogeneic hematopoietic stem cell transplantation | 12 (31) |
| Solid-organ transplantation | 13 (33) |
| Immunosuppressive therapy | 23 (59) |
| Neutropenia | 16 (41) |
| Diabetes mellitus | 19 (49) |
| Infection | |
| Proven/probable | 32 (82)/7 (18) |
| Fungal pathogen | |
| Mucoralesa | 19 (49) |
| Fusarium spp. | 12 (31) |
| Otherb | 8 (20) |
| Primary site of infection | |
| Lung | 23 (59) |
| Skin/Soft tissue | 9 (23) |
| Sinus | 6 (15) |
| Intra-abdominal | 1 (3) |
| Multiple sites | 21 (54) |
| First-line antifungal therapy | |
| Amphotericin B | 10 (26) |
| Voriconazole | 17 (44) |
| Posaconazole | 1 (3) |
| Micafungin | 8 (21) |
| No therapy | 3 (8) |
| Outcome | |
| Response to therapy (week 6) | 12 (31) |
| Mortality (week 4) | 18 (46) |
a
Rhizopus spp. (n = 10), Cunninghamella spp. (n = 4), Mucor spp. (n = 3), Lichtheimia spp. (n = 2).
b
Scedosporium apiospermum (n = 3), Scedosporium prolificans (n = 1), Purpureocillium lilacinum (n = 2), Paecilomyces variotii (n = 1), Scopulariopsis spp. (n = 1).