TABLE 3.
Response to amphotericin B therapy at week 6 for various MIC cutoffs
MIC cutoff (μg/ml) | Response rate (no. [%]) (n = 10a) |
P value | |
---|---|---|---|
MIC ≤ cutoff | MIC > cutoff | ||
0.25 | 2/2 (100) | 3/8 (38) | 0.40 |
0.5 | 5/6 (83) | 0/4 (0) | 0.05 |
1 | 5/7 (71) | 0/3 (0) | 0.17 |
2 | 5/7 (71) | 0/3 (0) | 0.17 |
4 | 5/8 (63) | 0/2 (0) | 0.44 |
Rhizopus spp. (n = 6), Mucor spp. (n = 1), Cunninghamella spp. (n = 1), Scedosporium apiospermum (n = 1), Purpureocillium lilacinum (n = 1).