FIG 2.

Paired analyses of viral-load and CD4⁺ T-cell count changes before and after drug resistance testing. We performed paired analyses with CD4⁺ T-cell counts (A and C) and viral-RNA loads (B and D) and with samples taken prior to but closest to the drug resistance test date (within 1 month) and with the paired samples from the patients closest to 6 months after drug resistance testing. (A and B) A total of 46 patients were analyzed for CD4⁺ T-cell count pairs before and after detection of drug resistance by Sanger sequencing (A) and 42 patients for plasma viral-RNA loads before and after detection of drug resistance by Sanger sequencing (B). (C and D) Paired samples 1 month before and 6 months after drug resistance testing were also analyzed for patients with no detectable HIV drug resistance by Sanger sequencing, i.e., 13 patients/paired samples for CD4⁺ T-cell counts (C) and 15 patients/paired samples for plasma viral loads (D). The P values were calculated using paired one-tailed t tests.