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In vivo efficacy test of three novel compounds, molucidin, ML-2-3, and ML-F52. (A) Parasitemia changes for 20 days postinfection. Five consecutive daily shots of 30 mg/kg of each compound were inoculated (intraperitoneally) as well as vehicle-treated mice (Neg Control). ML-F52-treated mice showed no parasitemia for 20 days. (B) Survival rate curve for 20 days postinfection. ML-F52-treated group showed 100% cure for 20 days postinfection.
