TABLE 1.
Relevant phenotypic characteristics of the panel of isolates tested
| Enzyme and/or characteristic | No. of isolates with characteristic |
||||||
|---|---|---|---|---|---|---|---|
| A. baumannii | Citrobacter | E. coli | Enterobacter | Klebsiella | Proteeae | Serratia | |
| KPC | 3 | 10 | 10 | 20a | 2 | ||
| VIM | 4 | 10 | 10 | 20 | 1 | ||
| IMP | 5 | 10 | |||||
| NDM | 5 | 10 | 10 | 20b | 8 | 2 | |
| OXA-48 | 2 | 10 | 10 | 20c | 1 | 2 | |
| Porin loss + AmpCd | 10 | ||||||
| Porin loss + ESBL | 10 | 20 | |||||
| Tigre + carbapenemase | 10 | 20 | |||||
| OXA-23/40/51d/58f | 39 | ||||||
| Tigrg + OXA-23 | 5 | ||||||
| Carbapenem susceptible | 10 | 2 | 10 | 10 | 10 | 5 | 3 |
a
Ten also with SHV ESBLs.
b
One also with OXA-48.
c
Eight also with ESBLs.
d
Hyperproduced.
e
Found tigecycline nonsusceptible (MIC of ≥2 μg/ml) by EUCAST criteria on previous BSAC agar dilution testing. Seven isolates had KPC, 9 had NDM, 7 had OXA-48, and 5 had VIM enzymes. All other groups were included without reference to prior tigecycline (or other tetracycline) results.
f
Nine or ten representatives of each OXA-carbapenemase type listed.
g
Found tigecycline nonsusceptible (MIC of ≥2 μg/ml) by EUCAST criteria for Enterobacteriaceae on previous BSAC agar dilution testing.