FIG 7.

Effects of antifungal treatment on cytokine production. Colonized rats received either amphotericin B or saline by intraperitoneal injection for 3 days and were subsequently infected with A. baumannii and sacrificed after 24 h. Concentrations of IL-17 (A and D), IL-2 (B and E), and IFN-γ (C and F) were measured in rat lung homogenates. The data are presented as means and SD. We compared lung cytokine levels between Candida-colonized rats treated for 3 days with amphotericin B (right bars) or not (left bars) without (A to C) or after (D to F) Acinetobacter infection. Student's t test; *, P < 0.05; ns, not significant.