TABLE 1.
Physical characteristics of TDF-MVC pod-IVRs used in the animal study
Physical characteristic | IVR configuration(s)a |
---|---|
TDF drug loading (mg)b | 230.8 ± 0.6 (6 pods) |
MVC drug loading (mg)b | 153.6 ± 1.4 (4 pods) |
Per-pod delivery channel cross-sectional area (mm2) | TDF, 0.79; MVC, 5.30c |
Each pod was coated with poly(vinyl alcohol); data represent total drug loading in IVR.
Data represent means ± SD.
For TDF, one 0.79-mm2 channel per pod; for MVC, three 1.77-mm2 channels per pod.