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In vitro and in vivo daily release rates and in vitro-in vivo correlation
| Drug (IVR formulation)a | Release rate (mg day−1)b |
IVIVCc | |
|---|---|---|---|
| In vitro | In vivo | ||
| TDF | 0.88 ± 0.04 | 0.31 ± 0.13 | 0.35 |
| MVC | 2.72 ± 0.08 | 0.67 ± 0.19 | 0.25 |
n = 4.
Data represent means ± SD.
IVIVC, in vitro-in vivo correlation; defined as in vivo release rate divided by in vitro release rate.
