TABLE 3.
Clinical and microbiological responses of patients receiving lock solution and their controlsa
| Response | Lock solution group (n = 30) | Control group (n = 60) | P value |
|---|---|---|---|
| Fever resolution (no./total no. [%]) | 19/19 (100) | 44/45 (98) | >0.99 |
| Days between bacteremia and fever resolution | 2 (1–9) | 2 (0–14) | 0.99 |
| Days between starting intervention and fever resolution for patients with fever resolution after starting intervention (catheter removal or lock therapy) | 3 (1–4) | 2 (1–13) | 0.28 |
| Microbiological parameters (no. [%]) | 30 (100) | 60 (100) | |
| Days between onset of bacteremia and microbiological eradication | 3 (1–10) | 3 (1–7) | 0.61 |
| Days between onset of bacteremia and catheter removal or exchange | 74 (4–240)b | 2 (1–8) | <0.0001 |
| Days between onset of bacteremia and starting intervention (catheter removal or lock therapy) | 4 (2–9) | 2 (1–8) | 0.0002 |
a
Data are presented as the median (range), unless otherwise specified.
b
In 4 patients, the CVCs were still in place at the time of data analysis.