TABLE 3.
Rifampin potentiates the activity of 4,5-linked aminoglycosides against wild-type P. aeruginosaa
| Antimicrobial | MIC (μg/ml) |
|
|---|---|---|
| −Rifampin | +Rifampin | |
| Paromomycin | 256 | 32 |
| Neomycin | 32 | 4 |
| Ribostamycin | 1,024 | 256 |
| Gentamicin | 2 | 2 |
| Amikacin | 2 | 2 |
| Kanamycin | 64 | 64 |
| Streptomycin | 32 | 32 |
| Erythromycin | 512 | 512 |
| Chloramphenicol | 32 | 16–32 |
| Nalidixic acid | 128 | 128 |
| Carbenicillin | 64 | 32–64 |
The MICs for the indicated antimicrobials were determined for wild-type P. aeruginosa PAO1 strain K767 in the absence (−) and presence (+) of one-half MIC of rifampin (8 μg/ml).