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Activity of liposomal amphotericin B, miltefosine, and compound 1 against BALB/c mice infected with L. donovani HU3 (n= 5)
| Tested compound | Administration | % inhibition | 95% CIa |
|---|---|---|---|
| Liposomal amphotericin B | 1 mg/kg i.v. (days 7, 9, and 11) | 99.52 | 0.28 |
| Miltefosine | 12 mg/kg p.o. × 5 days | 77.23 | 12.41 |
| Compound 1 | 50 mg/kg BIDb × 5 days | 20.93 | 8.34 |
CI, confidence interval.
BID, twice a day.
