Distribution of subjects according to the values of T-tau (x-axis) and Aβ1–42/P-tau ratio (y-axis) in the whole sample (A) and in the subsample of patients with MCI (B) taking into account the longitudinal change in diagnostic status, i.e., conversion to dementia (MCI-AD) or stability of MCI diagnosis (MCI-S). Abbreviations: T-tau, total tau; Aβ1–42, amyloid-beta peptide; P-tau, 181Thr-phosphorylated-tau; MCI, mild cognitive impairment; MCI-AD, MCI subjects who progressed to Alzheimer's disease.