Table 4.

Cross-validation values for sensitivity, predictive values, and accuracy in the classification of AD and controls

CSF biomarker	Cutoff	AD (n = 41)		Controls (n = 41)		(AD × controls)
Sensitivity, %	Predictive value, %	Sensitivity, %	Predictive value, %	Accuracy, %
Aβ1–42	<416.0 pg/mL	80	68	63	76	72
Phosphorylated tau	>36.1 pg/mL	60	72	78	67	69
Total tau	>76.7 pg/mL	79	66	60	75	69.6
Aβ1–42/P-tau	<9.53	87	79.5	78	86	82.7
Aβ1–42/T-tau	<4.13	72	87.5	90	76.5	81

Abbreviations: AD, Alzheimer's disease; CSF, cerebrospinal fluid; Aβ_1–42, amyloid-beta peptide; P-tau, ¹⁸¹Thr-phosphorylated-tau; T-tau, total tau.

NOTE. Biomarker concentrations are given in pg/mL.