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. 2015 Oct 9;1(4):403–411. doi: 10.1016/j.dadm.2015.09.002

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© 2015 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 3 — Temporal development of CSF Aβ₄₂ levels for each individual divided according to follow-up cognitive diagnoses n = 36 individuals. CSF: all occasions = 23 individuals, baseline + year 5 = 9 individuals, baseline + year 9 = 4 individuals. Cognitive groups: (A) Normal-Normal n = 26 individuals, (B) Normal-MCI n = 3 individuals, (C) Normal-AD/DLB n = 5 individuals, and (D) Normal-other dementia n = 2 individuals. Green dotted line represents change of mean value for each group with more than four participants. Red dotted line indicates cutoff 192 ng/L, suggested by Shaw et al [29]. Abbreviations: CSF, cerebrospinal fluid; Aβ₄₂, β-amyloid 42; MCI, mild cognitive impairment; AD, Alzheimer's disease; DLB, dementia with Lewy bodies.