Figure 1.
Patient selection. All lung transplant patients (n = 210) from March 2005 to February 2010 were considered for inclusion in the retrospective study cohort. n = 24 were excluded due to early death (within 3 months of transplantation) and n = 14 were excluded for development of restrictive allograft syndrome (RAS) within 3 years of transplantation. Of the remaining patients, n = 25 (13.4%) developed BOS within 3 years of transplantation and were selected as our study population. n = 147 remained free from BOS at 3 years, and n = 25 were selected as a case‐controlled group. The nested case–control group was matched for type of transplant, age, sex, and number of acute rejection episodes. BOS, bronchiolitis obliterans syndrome.