Table 2.
P ST | ||||||
---|---|---|---|---|---|---|
Metabolic chains | Protein complexes | Signalling cascades | ||||
ρ | P value | ρ | P value | ρ | P value | |
Brain | 0.023 | 0.090 | 0.034 | 0.012 | 0.038 | 0.0043 |
Kidney | 0.049 | 2.1 × 10−4 | 0.045 | 6.5 × 10−4 | 0.007 | 0.62 |
Liver | 0.140 | <2.2 × 10−16 | 0.125 | <2.2 × 10−16 | 0.062 | 1.6 × 10−5 |
Lung | 0.118 | <2.2 × 10−16 | 0.127 | <2.2 × 10−16 | 0.065 | 4.4 × 10−7 |
Muscle | 0.007 | 0.62 | 0.007 | 0.62 | 0.009 | 0.58 |
Skin | 0.034 | 0.0082 | 0.032 | 0.013 | 0.026 | 0.043 |
Ovary | −0.025 | 0.053 | −0.040 | 0.0024 | −0.009 | 0.53 |
Testis | 0.045 | 3.1 × 10−4 | 0.039 | 0.0016 | 0.010 | 0.47 |
Embryo | 0.082 | 1.1 × 10−10 | 0.057 | 1.0 × 10−5 | 0.081 | 1.8 × 10−10 |
Between−species variance (σb) | ||||||
Brain | 0.002 | 0.90 | 0.004 | 0.83 | 0.028 | 0.065 |
Kidney | 0.025 | 0.091 | 0.024 | 0.10 | −0.011 | 0.47 |
Liver | 0.082 | 2.0 × 10−8 | 0.076 | 1.4 × 10−7 | 0.028 | 0.085 |
Lung | −0.092 | 1.1 × 10−12 | −0.115 | <2.2 × 10−16 | −0.018 | 0.19 |
Muscle | −0.026 | 0.091 | −0.021 | 0.17 | −0.022 | 0.16 |
Skin | −0.001 | 0.93 | 0.005 | 0.77 | 0.028 | 0.058 |
Ovary | −0.022 | 0.13 | −0.038 | 0.0080 | 0.003 | 0.87 |
Testis | 0.053 | 4.0 × 10−5 | 0.044 | 8.9 × 10−4 | 0.011 | 0.43 |
Embryo | 0.041 | 0.0031 | 0.019 | 0.17 | 0.031 | 0.036 |
Within−species variance (σw) | ||||||
Brain | −0.170 | <2.2 × 10−16 | −0.156 | <2.2 × 10−16 | −0.131 | <2.2 × 10−16 |
Kidney | −0.284 | <2.2 × 10−16 | −0.239 | <2.2 × 10−16 | −0.167 | <2.2 × 10−16 |
Liver | −0.304 | <2.2 × 10−16 | −0.277 | <2.2 × 10−16 | −0.162 | <2.2 × 10−16 |
Lung | −0.254 | <2.2 × 10−16 | −0.181 | <2.2 × 10−16 | −0.191 | <2.2 × 10−16 |
Muscle | −0.313 | <2.2 × 10−16 | −0.281 | <2.2 × 10−16 | −0.167 | <2.2 × 10−16 |
Skin | −0.365 | <2.2 × 10−16 | −0.304 | <2.2 × 10−16 | −0.227 | <2.2 × 10−16 |
Ovary | −0.234 | <2.2 × 10−16 | −0.181 | <2.2 × 10−16 | −0.175 | <2.2 × 10−16 |
Testis | −0.268 | <2.2 × 10−16 | −0.223 | <2.2 × 10−16 | −0.154 | <2.2 × 10−16 |
Embryo | −0.321 | <2.2 × 10−16 | −0.277 | <2.2 × 10−16 | −0.202 | <2.2 × 10−16 |