Table 2. Coefficients and HRs (95% CI) of models and values of risk scores for predicting incident diabetes in the exploration cohort using the Cox proportional hazards model.
Concise score |
Accurate score |
Score | |||
---|---|---|---|---|---|
HR (95% CI) | Coefficient | HR (95% CI) | Coefficient | ||
Age (years) | |||||
18–29 | Ref. | Ref. | 0 | ||
30–39 | 2.03 (1.61–2.56) | 0.71 | 1.74 (1.38–2.18) | 0.55 | 6 |
40–49 | 3.26 (2.63–4.05) | 1.18 | 2.66 (2.15–3.30) | 0.98 | 10 |
50–59 | 3.20 (2.58–3.96) | 1.16 | 2.59 (2.09–3.21) | 0.95 | 10 |
60–69 | 3.28 (2.62–4.10) | 1.19 | 2.90 (2.32–3.62) | 1.06 | 11 |
≥70 | 3.16 (2.48–4.03) | 1.15 | 2.94 (2.30–3.75) | 1.08 | 11 |
Gender (Men) | 1.34 (1.23–1.44) | 0.29 | 1.14 (1.05–1.23) | 0.13 | 2 |
BMI (kg/m2) | |||||
<24.0 | Ref. | Ref. | 0 | ||
24.0–28.0 | 1.68 (1.56–1.81) | 0.52 | 1.44 (1.33–1.55) | 0.36 | 4 |
≥28.0 | 2.68 (2.48–2.91) | 0.99 | 2.08 (1.91–2.25) | 0.73 | 9 |
Family history of diabetes | 1.66 (1.48–1.86) | 0.51 | 1.45 (1.29–1.64) | 0.37 | 4 |
Education (high school or below) | 1.34 (1.16–1.55) | 0.29 | 1.38 (1.20–1.60) | 0.32 | 3 |
Blood pressure (mmHg) | |||||
SBP < 120 or DBP < 80 | Ref. | Ref. | 0 | ||
120 ≤ SBP < 140 or 80 ≤ DBP < 90 | 1.25 (1.14–1.38) | 0.22 | 1.17 (1.06–1.29) | 0.16 | 2 |
SBP ≥ 140 or DBP ≥ 90 or using anti-hypertensive drugs | 1.62 (1.47–1.78) | 0.48 | 1.37 (1.24–1.51) | 0.31 | 4 |
Resting heart rate (bpm) | |||||
<70 | Ref. | Ref. | 0 | ||
70–79 | 1.16 (1.08–1.25) | 0.15 | 1.07 (0.99–1.15) | 0.07 | 1 |
80–89 | 1.36 (1.25–1.49) | 0.31 | 1.15 (1.06–1.25) | 0.14 | 2 |
≥90 | 1.77 (1.58–1.98) | 0.57 | 1.26 (1.13–1.42) | 0.23 | 4 |
FPG (mmol/L) | |||||
<5.6 | Ref. | 0 | |||
5.6–6.1 | 2.94 (2.73–3.16) | 1.08 | 11 | ||
6.1–6.9 | 7.05 (6.59–7.55) | 1.95 | 20 | ||
TG ≥ 1.70 mmol/L or using lipid-lowering drugs | 1.41 (1.33–1.49) | 0.34 | 3 | ||
AUC of the risk scores | 0.67 | 0.77 |
Key: BMI – body mass index; SBP – systolic blood pressure; DBP – diastolic blood pressure; FPG – fasting plasma glucose; TG – Triglyceride; AUC – area under the receiver operating characteristic curve.