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| Compound # | Anti-promastigote activity IC50 (μM)a | Cytotoxicity CC50 on mammalian COS7 cell linesb | Selectivity Index (SI)c |
|---|---|---|---|
| 4 | 4.21 ± 0.21 | 390.58 ± 3.15 | ~100 |
aIC50 values are average of two independent screenings expressed as an average ± standard error.
bCC50 on COS7 cells.
cSelectivity index is: CC50 against COS7/IC50 against promastigote.
dND: Not determined.
