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. 2016 May 25;6:26583. doi: 10.1038/srep26583

Figure 1. Schematic representation of the terpenoid indole alkaloid (TIA) biosynthetic pathway.

Figure 1

Enzyme abbreviations: DXS, 1-deoxy-D-xylulose-5-phosphate synthase; IPP, isopentenyl pyrophosphate; DMAPP, dimethylallyl pyrophosphate; IDI1, isopentenyl diphosphate isomerase 1; CPR, cytochrome P450 reductase; G10H, geraniol 10-hydroxylase; UGT8, UDP-sugar glucosyltransferase 8, 7-DLH, 7-deoxyloganic acid hydroxylase; LAMT, loganic acid O-methyltransferase; SLS, secologanin synthase; AS, anthranilate synthase; TDC, tryptophan decarboxylase; STR, strictosidine synthase; SGD, strictosidine glucosidase; T16H, tabersonine 16-hydroxylase; 16OMT, 16-hydoxytabersonine-O-methyltransferase; NMT, N-methyltransferase; D4H, desacetoxyvindoline-4-hydroxylase; DAT, deacetylvindoline-4-O-acetyltransferase; and PRX, vacuolar class III peroxidase.