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. 2016 May 25;6:26556. doi: 10.1038/srep26556

Figure 3. CDR-H3 cluster among carrier children.

Figure 3

(A,B) A single 27-member cluster was identified from carrier 2-occurrence clones. This cluster was best associated with HBV-infection. Vertices in the graph represent CDR-H3 clones, and connecting edges equal in indel-free Hamming distance 1. (C) The 27-member cluster was extended by indel-free Hamming distance 1 to connect other similar sequences among the most abundant 20% of clones. This resolved into a new 222-member cluster. Most members were restricted to carriers only, as depicted in solid circles. (D) The extended cluster appeared mostly in the carrier children. Each child had at least one repertoire that contributed more than 0.1% of reads to the connected web.