Table 3.

Distribution of Serious Drug-Related Adverse Events.^*

Event	Earlier ART	Later ART number of events	Total
Hepatic toxicity	107	105	212
Anemia	69	43	112
Mitochondrial toxicity	16	19	35
Cutaneous toxicity	10	22	32
Electrolyte disorders	12	14	26
Metabolic disorders	11	10	21
Neutropenia	7	14	21
Peripheral neuropathy	8	8	16
Gastrointestinal disorders	3	6	9
Neuropsychiatric disorders	6	1	7
Ocular toxicity	1	2	3
Hypothyroidism	0	1	1
Ototoxicity	1	0	1
Total	251	245	496

^*Serious adverse events were defined as those that were grade 3 or higher. Drugs included antiretroviral agents.