Table 1.
Comparison of baseline characteristics and clinical outcome 12 months after acute hospitalization
| Total sample | No anemia | Anemia | |
|---|---|---|---|
| N=884 | 474 (54%) | 410 (46%) | |
| Demographics | |||
| Age | 84 (6.2) | 84 (6.2) | 85 (6.2) |
| Male | 284 | 119 (42%) | 165 (58%)** |
| Women | 600 | 355 (59%) | 245 (41%) |
| Receive home care | 362 (40%) | 196 (42%) | 166 (38%) |
| Admitted after a fall | 367 (41%) | 137 (38%) | 190 (44%) |
| Admission diagnosis | |||
| Hip fracture | 66 (8%) | 15 (3%) | 51 (12%)** |
| Other acute trauma | 258 (29%) | 144 (30%) | 114 (28%) |
| Infection | 218 (25%) | 116 (25%) | 102 (25%) |
| Heart diseasee | 133 (15%) | 68 (14%) | 65 (16%) |
| Other medical/pulmonary diseases | 209 (23%) | 131 (28%) | 78 (19%) |
| Geriatric assessment | |||
| More than 5 diagnosis | 528 (63%) | 266 (56%) | 262 (64%)** |
| Use > 5 drugs | 705 (81%) | 361 (76%) | 344 (84%)* |
| Barthel index | 75 (60-85) | 80 (60-90) | 75 (60-85)** |
| Depression, GDS | 7 (4-12) | 7 (4-12) | 7 (3-12) |
| Cognition, MMSE | 26 (23-28) | 26 (23-28) | 26 (23-28) |
| Nutrition, MNA-SF | 10 (8-12) | 10 (8-12) | 10 (8-12) |
| Laboratory assessments | |||
| Hb, g/dL | 12.3 (7.6-19.0) | 13.4 (12.0-19.0) | 11.0 (7.6-12.9)** |
| Hb men, g/dL | 12.4 (7.6-19.0) | 13.8 (13.0-19.0) | 11.3 (7.6-12.9)** |
| Hb women, g/dL | 12.3 (8.6-18.0) | 13.2 (12.0-18.0 | 11.0 (8.6-11.9)** |
| Severe anemi (<10.6g/L)a | 130 (15%) | 0 | 130 (32%)** |
| MCVfL | 94 (6) | 94 (6) | 94 (6) |
| VitB12, pmol/L | 506 (331-780) | 471 (319 -772) | 574 (361-826)** |
| Folate, nmol/L | 16.2 (5.3-45..0) | 13.2 (5.0-45.3) | 14.8 (5.0-45.3) |
| Ferritin µg/L | 184 (104-350) | 179 (101-333) | 193 (107-366) |
| Transferrin receptor, ml/L | 3.4 (2.7-4.4) | 3.3 (2.7-4.2) | 3.4 (2.7-4.6) |
| CRP, mg/L | 18 (1-331) | 13 (1-217) | 27 (1-331)** |
| Renal insufficiencyb | 362 (41%) | 157 (34%) | 205 (50%)** |
| NT pro-BnP, pmol/L | 92 (35-266) | 69 (28-188) | 134 (45-377)** |
| 1 year follow up | |||
| >2 hospital admissions | 229 (33%) | 144 (31%) | 15 (35%) |
| Dead | 150 (17%) | 74 (16%) | 77 (19%) |
Continuous parameters are presented as mean (standard deviation) and median (interquartile range), categorical data are presented as numbers (percentages)
GDS Geriatric Depression scale, range 1-30, MMSE Mini Mental Status Examination, MNA-SF Mini Nutritional Assessment- Short Form, CRP C-reactive protein, NT pro- BnP N-Terminal pro brain-type natriuretic peptide, Hb Hemoglobin, MCV mean corposcular volume.
*p<0.05, **p<0.01 when the group of non-anemic and anemic patients were compared.
aSevere anemia defined as Hb concentration in the lower anemia tertile.
‡Renal insufficiency was defined as e-GFR (described in methods) < 60 mL/min/1.73 m2.