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. 2016 Apr 28;13(5):365–373. doi: 10.7150/ijms.14989

Figure 5.

Figure 5

EphrinB2-Fc restored K562-R cells sensitivity to IM. A. Expression of EphB4 and p-EphB4 in K562, K562-R and K562-R-EphB4-sh cell lines. Expression of ephrinB2 in K562, K562-R and K562-R-EphB4-sh. Expression of proteins analyzed by Western blotting. B. Comparison of IC50 in K562-R, ephrinB2-Fc (4µg/ml), K562-R+ IgG-Fc (0.4µg/ml), and control groups in different concentrations of IM by CCK8 assay. C. Apoptosis percentage for the K562-R cell line treatment with EphrinB2-Fc, IgG-Fc, and blank control by flow cytometry.