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. Author manuscript; available in PMC: 2016 May 25.
Published in final edited form as: Biochim Biophys Acta. 2010 Sep 16;1812(3):353–363. doi: 10.1016/j.bbadis.2010.09.004

Fig. 3.

Fig. 3

Phylogenetic conservation of kinases implicated in Tau phosphorylation. The sequence Figure shows the striking degree of amino acid conservation between human and zebrafish (A) GSK3β and (B) cdk5. Each panel shows the Human (upper) and zebrafish (lower) protein sequences, aligned using the ClustalW algorithm. Amino acids are shaded to show identical, conserved and non-similar residues. The catalytic domain of each kinase is indicated by underlining, and important Functional sites labeled as indicated.