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. Author manuscript; available in PMC: 2016 May 25.
Published in final edited form as: ACS Chem Neurosci. 2015 Mar 24;6(4):535–541. doi: 10.1021/acschemneuro.5b00055

Scheme 1.

Scheme 1

Improved radiosynthesis of [18F]CABS13 based on benzyloxymethyl precursor 1. (A) Reaction conditions and radiosynthesis results. (B) Plausible mechanism of trifluoroacetic acid mediated deprotection and formation of side products under aqueous acidic conditions.